| 摘要 |
1,156,005. Thioethers. FARBENFABRIKEN BAYER A.G. 27 June, 1966 [20 July, 1965], No. 28749/66. Heading C2C. The invention relates to a process of production of an o- or p-aminophenyl thioether, optionally substituted in the nucleus, wherein a nitrohalobenzene, optionally substituted in the nucleus of the general formula in which Z 1 , Z 2 , Y 1 and Y 2 are identical or different, optionally substituted, radicals such as alkyl, alkenyl, alkinyl, cycloalkyl, cycloalkenyl, aryl, alkoxy, alkenyloxy, arloxy, alkylthio, arylthio or heterocyclic radicals, or hydrogen; Y 1 and Y 2 may also represent halogen; and X represents halogen, is reacted in the molar ratio of about 1 to about 2À5 with sodium sulphide in an aqueous suspension at a temperature of from about 0‹ C. to about 200‹ C., and, without isolating the aminothiophenol, the aqueous alkali solution of the resulting aminothiophenol, the aqueous alkali solution of the resulting aminothiophenolate, optionally with the addition of a water-miscible organic solvent, is alkylated or arylated on to the sulphur atom at a temperature of from about 0‹ C. to about 100‹ C., and the aminophenyl thioether which is formed is isolated. Compounds claimed per se are those of the general formulµ in which R is CH 3 -, C 2 H 5 -, n- or i-C 3 H 7 , CH 2 =CH-CH 2 -, -CH 2 -CH 2 OH or -CH 2 - COOH. in which Q is hydrogen or chlorine, but at least one of the radicals Q is chlorine, in which one R is hydrogen and the other chlorine or both are hydrogen, Many examples are given. |
