摘要 |
Purification of Factor VIII containing solutions, such as blood plasma, by continuous flow electrophoresis. Hitherto, purification of such solutions his been performed by methods such as cryoprecipitation which however have the disadvantages of poor recovery. In our invention, this problem is overcome by adjusting the pH of a Factor VIII containing solution to be in a range where the stability of Factor VIII is not adversely affected (e.g. 6 to 9) and then subjecting the solution to continuous flow electrophoresis to give purified Factor VIII fractions. If desired, the fractions may be further purified. |