发明名称 4-Oxo-2-carboxyl quinoline derivatives used as antiallergic compounds
摘要 There are described compounds of formula I, <IMAGE> I in which R5 to R8 may be a variety of substituents, OR AN ADJACENT PAIR OF R5, R6, R7 and R8 form a chain -COCH=C(COOH)NRh-, OR ONE OF R5, R6, R7 and R8 form a group of formula II, <IMAGE> II in which Ra, Rb and Rc have the same significances as R5, R6, R7 and R8, X is an optionally interrupted or substituted hydrocarbon chain, Rg and Rh, which may be the same or different are each alkyl, alkenyl, phenyl-alkyl, alkanoyl, benzoyl or phenylalkanoyl, OR Rg and R8 and/or Rh and Rc in formula II, together form a chain -(CH2)n-, and n is 2, 3 or 4.
申请公布号 US4156726(A) 申请公布日期 1979.05.29
申请号 US19750635615 申请日期 1975.11.26
申请人 FISONS LTD 发明人 BROWN, ROGER C;CAIRNS, HUGH;PAYNE, ANTHONY R
分类号 C07D215/26;C07D215/28;C07D215/32;C07D215/48;C07D221/08;C07D221/10;C07D471/04;(IPC1-7):A61K31/47 主分类号 C07D215/26
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