发明名称 |
CHROMOGENIC SUBSTRATES FOR SERINE PROTEASES |
摘要 |
Serine proteases in a substance such as blood are determined by contacting the substance with a novel chromogenic or fluorgenic substrate for serine proteinases and spectrophotometrically measuring the quantity of a chromophore or fluorescent compound released from the substrate by serine proteases in the substance. The novel substrate has the amino acid sequence-ILe-A-Gly-Arg-wherein A is Asp or Glu substituted in the carboxylic group by esterification or amidation. The novel substrate increases sensitivity and accuracy of the determination. |
申请公布号 |
AU3077177(A) |
申请公布日期 |
1979.05.24 |
申请号 |
AU19770030771 |
申请日期 |
1977.11.18 |
申请人 |
KABI, AKTIEBOLAGET |
发明人 |
KARL GORAN CLAESON;LEIF ERIK AURELL;LEIF ROGER SIMONSSON |
分类号 |
C12Q1/37;C07K5/103;C12Q1/56;G01N33/68 |
主分类号 |
C12Q1/37 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|