发明名称 BASICALLY SUBSTITUTED 3,4-DIHYDRO-2H-ISOQUINOLIN-1-THIONES AND PROCESS FOR PREPARING THEM
摘要 <p>this invention relates to 3,4-aihydro-2H-isoquinoline-l-ones of the formula (X) wherein X1 represents hydrogen, a saturated or unsaturated, sraight-chained or branched alkyl radical having 1 to 6 carbon atoms or the phenyl radical, R2 represents a dialkylaminoalkyl radical of the formula wherein A represents a straight-chained or branched low molecular alkylene group and R5 and R6 are identical or different and represent straight-chained or branched, low molecular alkyl radicals and may form together with the nitrogen atom a 5-, 6or 7-membered ring, wherein one of the hydrocarbons is substituted by a hetero atom which may be substituted with hydrogen, C1-C4 alkyl or the phenyl radical, R3 and R4 are identical or different and represent hydrogen or a lower alkoxy group having 1 to 4 carbon atoms, and the physiologically tolerable salts thereof. The compounds have an antiarrhythmic activity and are suitable for treating disturbances of cardiac rhythm.</p>
申请公布号 CA1055027(A) 申请公布日期 1979.05.22
申请号 CA19750233696 申请日期 1975.08.13
申请人 HOECHST AKTIENGESELLSCHAFT 发明人 KUNSTMANN, RUDOLF;KAISER, JOACHIM
分类号 C07D217/22;C07D217/24;C07D295/125;(IPC1-7):07D401/06 主分类号 C07D217/22
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