| 发明名称 |
(R)-({31 )-3-{55 {8 2-(P-hydroxyphenyl)-1-methylethyl{9 -aminomethyl{56 -3,4-dihydro-2H-1,5-benzodioxepin-3-ol |
| 摘要 |
The isomer (R)-(-)-3-{[2-(p-hydroxyphenyl)-1-methylethyl]-aminomethyl}-3,4-dihydr o-2H-1,5-benzodioxepin-3-ol and its non-toxic acid addition salts is unexpectedly more potent in the reduction of elevated interocular pressure in mammals than its enantiomorph or the racemate thereof.
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| 申请公布号 |
US4156010(A) |
申请公布日期 |
1979.05.22 |
| 申请号 |
US19770864171 |
申请日期 |
1977.12.27 |
| 申请人 |
MERCK & CO INC |
发明人 |
HIRSCHMANN, RALPH F |
| 分类号 |
C07D321/10;(IPC1-7):A61K31/33;A61K31/74;C07D319/08 |
主分类号 |
C07D321/10 |
| 代理机构 |
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