| 摘要 |
PURPOSE:To prepare an antibiotic substance, sisomicin, by the cultivation of Micromonospora cyaneogranulata. CONSTITUTION:Sisomicin-producing bacteria belonging to Micromonospora cyaneogranulata, e.g. Micromonospora cyaneogranulata A10030 strain (FERM-P No.4276) is cultured in a medium, and sisomicin is separated from the medium. The culturing is pref. carried out in an aerated deep-tank fermentor, pref. at 26-32parag.C for 3-5 days. Bacteria belonging to Micromonospora inyoensis, Micromonospora jionensis, or Micromonospora grisea, also produce the anitbiotic substance, sisomicin. |
