发明名称 Substituted isocytosines having histamine H{HD 2{B -antagonist activity
摘要 The compounds are substituted isocytosines which are histamine H2-antagonists. Two specific compounds of the present inventon are 2-[2-(5-methyl-4-imidazolylmethylthio)ethylamino]-5-(3-pyridylmethyl)- 4-pyrimidone and 2-[2-(3-bromo-2-pyridylmethylthio)ethylamino]-5-(4-pyridylmethyl)-4-py rimidone.
申请公布号 US4154834(A) 申请公布日期 1979.05.15
申请号 US19770861144 申请日期 1977.12.16
申请人 SMITH KLINE & FRENCH LABORATORIES LTD 发明人 BROWN, THOMAS H;DURANT, GRAHAM J;GANELLIN, CHARON R
分类号 C07D239/56;C07D401/06;C07D401/14;(IPC1-7):A61K31/50;C07D239/36 主分类号 C07D239/56
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