发明名称 S-HETEROCYCLIC DERIVATIVES OF PHOSPHINE OR PHOSPHITE GOLD MERCAPTIDES
摘要 <p>S-Heterocyclic derivatives of phosphine or phosphite gold mercaptides of the formula: FORMULA I in which: R1 is lower alkyl, lower alkoxy, phenyl or phenoxy, with each alkyl or alkoxy having from one to three carbon atoms; X is S, NH, NCH3 or O; R2 and R3 are hydrogen or together from a 1,2-benzo radical; and ? indicates an optional double bond are disclosed. These compounds are prepared by reaction of an heterocyclic mercaptain compound with an appropriate phosphine or phosphite gold halide in the presence of alkali. These compounds have been found to have anti-arthritic activity.</p>
申请公布号 CA1054609(A) 申请公布日期 1979.05.15
申请号 CA19740206060 申请日期 1974.07.31
申请人 SMITH KLINE & FRENCH CANADA LTD 发明人 WEINSTOCK J;SUTTON B
分类号 C07D235/24;A61K31/66;A61P29/00;C07F9/02;C07F9/143;C07F9/145;C07F9/50;C07F9/62;C07F9/6506;C07F9/653;C07F9/6539;C07F9/6541;(IPC1-7):07F9/65 主分类号 C07D235/24
代理机构 代理人
主权项
地址