| 摘要 |
The compounds are of the class of thiepin derivatives, more particularly thiepin derivatives, which may be substituted in the benzene rings by alkyl, alkoxy or alkylthio, further substituted in 11 positions by piperazinyl which may be fully substituted, and in 10-position by hydroxy or o-alkanoyl, and acid addition salts thereof. The compounds are useful as anti-emetic, anaesthesia-potentiating, reflex-inhibiting and catatonia inducing agents. An illustrative embodiments is 11-(4-methyl-1-piperazinyl)-10,11-dihydrodibenzo[b,f]thiepin-10-ol. |
