| 摘要 |
NEW MATERIAL:Phenylacetamide derivatives of formula I (R1 and R2 are 1-3C alkyl groups, etc.; R3 and R4 are Hor1-3C alkyl groups; X is 1-3C alkyl group, 1-3C alkoxy, or 1-3C acyloxy group, or halogen; Y is H or 1-3C alkoxy group; m and m2 are O or integers <= 2) and their acid salts. EXAMPLE:N-(2-Diethylaminoethyl)-N-phenethyl-4-methoxyphenylacetamide. USE:Medicines having central nervous system depressing, analgesic, and antihistaminic actions. PROCESS:Compounds of formula II are heated with equimolar or slightly excess molar amounts of reactive functional derivatives of compounds of formula III in an inert solvent for several hr, and the reaction mixture is washed with an aqueos led in vacuo to give the compounds of formula I. |
