发明名称 PROCESS FOR PRODUCING CARBOXAMIDO-THIAZOLE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AS ACTIVE AGENTS
摘要 Cpds. of formula (I) and their addn. salts with strong mineral acids or organic sulphonic acids are new (where R1, R2 and R3 are each H or 1-6C alkyl). They are prepd. by reacting the corresp. acid halide with an amine deriv. of formula R2NH-OR3. (I) have antilipolytic, vasodilatory and hypoglycaemic activities, they are useful in treatment of acute or chronic hyperlipaemia, coronary insufficiencies, atheromatose cardiac insufficiencies, chronic angina, hypertensive functional troubles and prediabetic and diabetic states.
申请公布号 HU173383(B) 申请公布日期 1979.04.28
申请号 HU1976RO00882 申请日期 1976.02.27
申请人 ROUSSEL UCLAF,FR 发明人 POITTEVIN,ANDRE,FR;FOURNEX,ROBERT,FR;DAGNAUX,MICHEL,FR
分类号 A61K31/426;C07D277/56 主分类号 A61K31/426
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