摘要 |
Compounds of the formula <IMAGE> wherein X and Y are the same or different and are hydrogen, fluoro, chloro, bromo, alkyl of one to six carbon atoms, inclusive, alkoxy of one to six carbon atoms, inclusive, nitro, cyano, amino, trifluoromethyl, <IMAGE> wherein R1 is alkyl of one to six carbon atoms, inclusive, <IMAGE> wherein R2 and R3 are the same or different and are hydrogen or alkyl of one to three carbon atoms inclusive, or CO2Q where Q is alkyl of one to six carbon atoms, inclusive, hydrogen or a physiologically acceptable metal or amine cation; and R is hydrogen, alkyl of one to eight carbon atoms, inclusive, -CH2)m phenyl wherein m is 0, 1 or 2 or (CH2)nNR4R5 wherein n is 1 or 2, and R4 and R5 are the same or different and are alkyl of one to three carbon atoms, inclusive, and a physiologically acceptable metal or amine cation; and physiologically acceptable acid addition salts thereof are formulated into pharmaceutical compositions suitable for oral, parenteral or inhalation administration which are used as prophylactic inhibitors of allergic manifestations in sensitized mammals.
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