发明名称 |
3-Acyl-4-ethyl-2-oxazolones and oxazolidinones |
摘要 |
This invention relates to the preparation of optically active d-2-aminobutanol by catalytic asymmetric reduction of appropriate dehydro precursors to produce selectively the desired isomer. The same substrates can also be used to prepare the dl-mixture using optically inactive catalysts. The novel substituted-4-ethyl-4-oxazolin-2-one and substituted-4-ethyl-2-oxazolidinone compounds of this invention are useful as intermediates in the production of the antituberculosis drug ethambutol (Myambutol TM ).
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申请公布号 |
US4150030(A) |
申请公布日期 |
1979.04.17 |
申请号 |
US19770786906 |
申请日期 |
1977.04.12 |
申请人 |
AMERICAN CYANAMID COMPANY |
发明人 |
SINGH, BALWANT |
分类号 |
C07D263/26;C07D263/38;C07F15/00;(IPC1-7):C07D263/26 |
主分类号 |
C07D263/26 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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