| 摘要 |
<p>Preparations for local treatment of acne vulgaris, particularly in the form of ointments or face lotions, are prepared by mixing with a suitable cosmetic medicine an active substance prepared by (a) growing Coryne bacteria acnes in a liquid growth medium until the multiplication peak is passed, (b) obtaining acnecine inhibitor discharged by said bacteria into the surrounding medium from the bacteria as an inhibitor-containing liquid, (c) concentrating said inhibitor-containing liquid into a liquid concentrate, and (d) incorporating said liquid concentrate in a water-in-oil emulsion by adding emulsifiers. In ointment form the preparation normally contains about 20-40% of the liquid concentrate of step (d).</p> |
