摘要 |
NEW MATERIAL:Fortimicin KO of formula and its acid salt. USE:Antibacterial antibiotics. Effective against Gram-positive and Gram-negative bacteria, particularly a certain type of Escherichia coli resistant to kanamycin, Gentamicin, etc. PROCESS:Microorganisms which belong to the Micromonospora species and have Fortimicin KO producing ability are cultured in a medium to accumulate Fortimicin KO in the cultured substance, from which the Fortimicin KO is collected. Micromonospora Olivoasterospora MK-70, etc. may be preferred as the microorganisms. |