发明名称 Inhibition of platelet aggregation with selected phosphoric acid esters
摘要 A process for inhibiting platelet aggregation or thrombus formation by the addition of a member selected from the group consisting of a compound of the formula: <IMAGE> WHEREIN X is an alkyl or alkenyl chain having 2-8 carbon atoms, one of which carbon atoms may be in the form of a carbonyl group, Y is H, alkyl, dialkylaminoethyl, aryl, aralkyl or aryl and aralkyl substituted with one or more R, and R is H, lower alkyl, lower alkoxy, halogen, CF3, NO2, OH, CN, COOR1, <IMAGE> NHCOR1, NR1R2 or <IMAGE> where R1 and R2 are each selected from the group consisting of H and lower alkyl; R, R1 and R2 being the same or different and n is 0-5; and pharmaceutically acceptable salts thereof, to in vivo and in vitro platelet systems.
申请公布号 US4148878(A) 申请公布日期 1979.04.10
申请号 US19770864020 申请日期 1977.12.23
申请人 NELSON RESEARCH & DEVELOPMENT COMPANY 发明人 NELSON, ERIC L.
分类号 A61K31/66;(IPC1-7):A61K35/14;A61K31/68 主分类号 A61K31/66
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