| 摘要 |
The invention provides certain dibenzo[a,d]cycloocten-5,12-(and 6,12)- imines and their substituted derivatives and pharmaceutically acceptable salts of such compounds, methods of preparing such compounds and pharmaceutically acceptable compositions containing them. The compounds, the free-base forms of which have the formula: <IMAGE> where R, R<1> and R<2> are hydrogen or certain hydrocarbon residues, and R<3> and R<4> are hydrogen, halogen, alkoxy, CF3S-, -CN, -COOH or -OH, are useful as antianxiety agents, as muscle relaxants and in the treatment of extrapyramidal disorders such as in Parkinson's disease. |
