发明名称 ARYLSULFONYLCARBAMOYL-1,3-DICARBONYLALICYCLIC AND ARYLSULFONYLCARBAMOYL-1,3-DICARBONY-LACYCLIC COMPOUNDS
摘要 <p>ARYLSULFONYLCARBAMOYL-1,3-DICARBONYLALICYCLIC AND ARYLSULFONYLCARBAMOYL-1,3-DICARBONYL- ACYCLIC COMPOUNDS A new class of arylsulfonylcarbamoyl-1,3-cyclohexanediones and arylsulfonylcarbamoyl-1,3-dicarbonylacyclic compounds are disclosed. These substances have hypoglycemic or hyperglycemic properties and are of value in controlling abnormal blood sugar levels. The arylsulfonylcarbamoyl derivatives of 1,3-dicarbonylalicyclic and acyclic compounds are prepared by reacting an arylsulfonylisocyanate with a 1,3-dicarbonylalicyclic or acyclic reactant. Typical embodiments are 2-(N-p-chlorobenzenesulfonylcarbamoyl)-5,5-dimethylcyclohexane-1,3-dione and 5-(1-ethylpropyl)-2-(N-p-chlorobenzenesulfonylcarbamoyl)-1,3-cyclohexanedione.</p>
申请公布号 CA1051924(A) 申请公布日期 1979.04.03
申请号 CA19750227783 申请日期 1975.05.26
申请人 BRISTOL-MYERS COMPANY 发明人 GRUNWALD, FREDERICK A.
分类号 A61K31/27;A61K;A61K31/18;A61K31/185;A61P3/08;C07C;C07C67/00;C07C301/00;C07C303/40;C07C311/51;(IPC1-7):07C143/78 主分类号 A61K31/27
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