发明名称 NEW 3,5-DISUBSTITUTED-1H-1,2,4-TRIAZOLE DERIVATIVES
摘要 The 3,5-disubstitited-1H-1,2,4-triazoles <IMAGE> in which: R is chosen from: hydrogen, (C1-4)alkyl, (C1-4)alkoxy, allyloxy, propargyloxy, trifluoromethyl, phenyl, fluoro, chloro and dimethylamino; R1 represents a (C1-4)alkyl group; R2 is chosen from: hydrogen, fluoro, chloro, (C1-4)alkyl, methoxy and ethoxy; R3 is chosen from: hydrogen, fluoro, chloro, (C1-4)alkyl and (C1-4)alkoxy; R and R3, taken together, represent a methylenedioxy group; on condition that, when R, R2 and R3 simultaneously represent hydrogen, R1 is not the methyl group; and also on condition that, when R2 and one of the groups R and R3 represent hydrogen, R1 and the other of the groups R and R3 are not simultaneously the methyl group; and their salts obtained with pharmaceutically acceptable acids are described. These compounds have antireproductive properties and act on the central nervous system.
申请公布号 ZA7802118(B) 申请公布日期 1979.03.28
申请号 ZA19780002118 申请日期 1978.04.12
申请人 GRUPPO LEPETIT SPA 发明人 OMODEI SALE A;CONSONNI P;GALLIANI G;LERNER L
分类号 A61K31/41;A61P25/00;C07D249/08;C07D317/68;C07D405/04 主分类号 A61K31/41
代理机构 代理人
主权项
地址