发明名称 WATER-SOLUBLE CORTICOIDS
摘要 Novel, water-soluble corticoids have the following formula <IMAGE> in which n denotes the figures 2 or 3, X denotes hydrogen, fluorine or chlorine and Y denotes hydrogen, an alkali metal atom or the N-methylglucamine radical. The compounds of the formula I are obtained by partially esterifying a corresponding 21-hydroxycorticoid with succinic anhydride or glutaric anhydride. Medicaments which contain a compound of the formula I as the active compound component can be used for the treatment of shock after an accident, burns, operation wounds, circulatory failure after intoxications, cardiac infarcts, pulmonary embolism and asthma.
申请公布号 ZA7801977(B) 申请公布日期 1979.03.28
申请号 ZA19780001977 申请日期 1978.04.06
申请人 SCHERING AG 发明人 WIECHERT R;KAPP J;KERB U
分类号 A61K31/57;A61P9/00;A61P11/00;C07J5/00;C07J51/00 主分类号 A61K31/57
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