摘要 |
Novel, water-soluble corticoids have the following formula <IMAGE> in which n denotes the figures 2 or 3, X denotes hydrogen, fluorine or chlorine and Y denotes hydrogen, an alkali metal atom or the N-methylglucamine radical. The compounds of the formula I are obtained by partially esterifying a corresponding 21-hydroxycorticoid with succinic anhydride or glutaric anhydride. Medicaments which contain a compound of the formula I as the active compound component can be used for the treatment of shock after an accident, burns, operation wounds, circulatory failure after intoxications, cardiac infarcts, pulmonary embolism and asthma. |