METHOD OF PREPARING 2,5-DISUBSTITUTED BENZAMIDES

摘要

2,5-disubstituted benzoic acids(I) were reacted with α-chloroacetonitrile to give corresponding cyanomethylester(II). And 2,5-disubstituted benzamides (III; A = low molecular mono- or di-alkylamino group. B = low molecular alkyl or alkylene group, n = 1 or 2, X = amino, mono- or di-alkylamino, alkyl or alkylene group) were prepd. by the reaction of II with H2N(CH2)nA.