发明名称 |
Antitumor antibiotics MA 144-M{HD 1 {B and MA 144-M{HD 2 |
摘要 |
New antitumor agents designated MA 144-M1 and MA 144-M2, which are anthracycline glycosides and inhibit the growth of gram-positive bacteria, e.g. Staphyococcus aureaus, Bacillus subtilis and Sarcina lutea, and inhibit the growth of animal tumors such as leukemia L 1210, P 388 and sarcoma 180 are produced by fermentation of MA 144-producing strains of streptomyces and by the chemical or enzymatic conversion of aclacinomycin A or cinerubin A.
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申请公布号 |
US4144329(A) |
申请公布日期 |
1979.03.13 |
申请号 |
US19770780730 |
申请日期 |
1977.03.24 |
申请人 |
MICROBIAL CHEM RES FOUND |
发明人 |
UMEZAWA, HAMAO;TAKEUCHI, TOMIO;NAGANAWA, HIROSHI;ISHIZUKA, MASAAKI, ALL OF;SHIBAMOTO, NORIO;OKI, TOSHIKAZU;INUI, TAIJI |
分类号 |
A61K31/70;A61K31/7028;A61K31/7034;A61K31/704;A61P31/04;A61P35/00;C07H15/252;C12P19/56;(IPC1-7):A61K31/71;C07H17/08 |
主分类号 |
A61K31/70 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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