2-Substituted-3-phenylindoles, their preparation, and pharmaceutical compositions containing them.

摘要

The invention relates to novel 3-phenyl-indoles of the formula <CHEM> wherein X and Y are independently hydrogen or halogen atoms; each n is 1, 2 or 3, Q is an oxygen atom or the group (H,OH), Z is a hydrogen atom, or provided that Q is an oxygen atom, Z can also be the group OR, wherein R is a hydrogen atom or a lower alkyl or loweralkoxy-loweralkyl group, "lower" indicating groups with 1-6 carbon atoms, m is 1 or 2 when Z is a hydrogen atom and m is O when Z is the group OR, to their preparation, and to pharmaceutical compositions containing them. These compounds have immunosuppressant activity and can be used for example in the treatment of rheumatoid arthritis.