| 摘要 |
<p>The invention discloses novel compounds of the general formula: in which the keto group is present at position 2 or 3 and in which X stands for oxygen, sulphur, the group or the group -CR8R9-; R1, R2, R3 and R4 represent hydrogen, hydroxy, halogen, alkyl (1-6 C), alkoxy (1-6 C), alkylthio(1-6 C) or trifluoromethyl; R7 stands for hydrogen or alkyl (1-4 C) alkylthio R8 and R9 stand for hydrogen or methyl. The compounds are useful as intemediates in the production of amino-substituted piperidino-derivatives having valuable central nervous system (CNS) activity, especially antidepressant activity.</p> |
