| 摘要 |
A non-toxic anionic resin selected from resins having a polymeric reticulated skeleton of styrenic or acrylic type, inert to the digestive enzymes, having a molecular weight higher than 1000 and containing ionizable amino groups, resins having a cellulosic reticulated skeleton modified by the introduction of free or substituted amino groups and resins having a polysaccharide reticulated skeleton modified by the introduction of free or substituted amino groups. The resin is capable of binding itself permanently to the biliary acids and is salified with an acid corresponding to the general formula: <IMAGE> wherein: R' represents a hydrogen atom, an alkyl group having 1 to 3 carbon atoms, a hydroxyalkyl group having 1 to 3 carbon atoms, R represents a chlorine atom or a group selected from p-chlorobenzoyl, p-bromobenzoyl and p-fluorobenzoyl, W represents a group selected from OH, -N(R''')-CH(R'')-(CH2)n-COOH and O-CH2-COOH wherein n represents a number from 0 to 5, R'' represents a hydrogen atom, a benzyl, a phenyl or a phenyl substituted with an OH group, a lower alkyl, a lower alkoxyl or a lower hydroxyalkyl group and R''' represents a hydrogen atom or a lower alkyl.
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