发明名称 Process for the preparation of novel benzylamines
摘要 The preparation of novel benzylamines of the formula I <IMAGE> in which the symbols R1 to R5 have the meanings stated in Claim 1, as well as their physiologically tolerated acid addition salts with inorganic or organic acids is described. The compounds of the formula I have valuable pharmacological properties, especially an antiulcer effect, a secretolytic, cough-suppressant effect and an effect enhancing the production of the surfactant or antiatelectasis factor in the alveoli. The compounds of the formula I are prepared by introducing the radical R5 into an appropriate compound in which R5 is hydrogen.
申请公布号 CH609036(A5) 申请公布日期 1979.02.15
申请号 CH19770005289 申请日期 1974.04.09
申请人 THOMAE, KARL (DR.) GMBH 发明人 DR. JOHANNES KECK;DR. KLAUS-REINHOLD NOLL;DR. HELMUT PIEPER;DR. GERD KRUEGER;DR. SIGFRID PUESCHMANN
分类号 C07C211/52;A61K31/137;C07C209/36;C07C209/60;C07C209/68;C07C211/27;C07C211/29;C07C211/49;C07C211/53;C07C213/08;C07C215/68;C07C217/84;C07C219/22;C07C227/06;C07C227/16;C07C227/18;C07C229/60;C07C233/43;C07C233/54;C07C253/30;C07C255/58;C07D221/24;C07D295/135;C07D295/155;C07D295/185;(IPC1-7):C07C87/50;C07C101/48;C07C103/00;C07D295/12 主分类号 C07C211/52
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