发明名称 2-Decarboxy-2-hydroxymethyl)-16-fluoro-PGE{HD 2 {B compounds
摘要 This invention comprises certain analogs of the prostaglandins in which the C-1 carboxyl is replaced by a primary alcohol. Also provided in this invention, are novel chemical processes useful in the preparation of the above prostaglandin analogs. These prostaglandin analogs exhibit prostaglandin-like activity, and are accordingly useful for the same pharmacological purposes as the prostaglandins. Among these purposes are blood pressure lowering, labor induction at term, reproductive cycle regulation, gastric antisecretory action, and the like.
申请公布号 US4139564(A) 申请公布日期 1979.02.13
申请号 US19770786153 申请日期 1977.04.06
申请人 THE UPJOHN COMPANY 发明人 NELSON, NORMAN A.
分类号 A61K31/045;A61K31/12;A61K31/557;A61K31/5575;A61P43/00;C07C57/30;C07C57/72;C07C67/00;C07C401/00;C07C405/00;C07D307/935;C07D319/06;(IPC1-7):C07C177/00 主分类号 A61K31/045
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