发明名称 4-Ureido-oleandomycin derivatives, process for their preparation and their use in pharmaceutical compositions.
摘要 <p>A compound of the formula: &lt;Chemistry id="chema01" num="0001"&gt;&lt;Image id="ia01" he="31" wi="62" file="IMGA0001.TIF" imgContent="chem" imgFormat="TIFF" inline="no" /&gt;&lt;/Chemistry&gt;wherein Y is a group of the formula: -NHCONHR&lt;Sub&gt;1&lt;/Sub&gt;, &lt;Chemistry id="chema02" num="0002"&gt;&lt;Image id="ia02" he="9" wi="65" file="IMGA0002.TIF" imgContent="chem" imgFormat="TIFF" inline="no" /&gt;&lt;/Chemistry&gt;-N=C=O or -NHCN; R is alkanoyl having two or three carbon atoms; R&lt;Sub&gt;1&lt;/Sub&gt; is hydrogen, pyridylmethyl, furylmethyl, thenyl, hydroxypyridyl, phenyl, benzyl, or phenyl or benzyl substituted by methyl, chloro, fluoro, methoxy, amino or trifluoromethyl; and X is methyl, methoxy, fluoro, chloro or trifluoromethyl; or a pharmaceutically acceptable acid addition sait thereof when Y is other than -N - C= 0.</p><p>A process for preparing these compounds and pharmaceutical compositions containing them.</p>
申请公布号 EP0000656(A1) 申请公布日期 1979.02.07
申请号 EP19780300186 申请日期 1978.07.24
申请人 PFIZER INC. 发明人 BRIGHT, GENE MICHAEL
分类号 A61K31/70;A61K31/7042;A61K31/7048;A61P31/04;C07H17/08;(IPC1-7):07H17/08;61K31/70 主分类号 A61K31/70
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