发明名称 Acetylated water soluble gluco-peptide prepn. - from pseudomonas aeruginosa; used as antiinflammatories, antibacterials, and immunostimulant(s)
摘要 <p>Water soluble acetylated glucopeptides (I) are prepd. from lysed Pseudomonas aeruginosa cells. They have a molecular weight between 500 and 200,000 and contain >=20% buiretogenic material and >=25% neutral monosaccharides. (I) contains no diaminopimelic acid and has UV absorption maxima at 210 and 260 mu. Glucoproteins of mol. wt. >300,000 extracted from Lysed P. aeruginosa are submitted to acetolysis, usually with a mixt. of acetic anhydride, acetic acid, and sulphuric acid. The crude acetylated prod. is treated with an organic solvent, such as chloroform, and the aq. phase undergoes diafiltration using a porous membrane which retains material of mol. wt. >500. The soln. not passing the membrane contains (I).</p>
申请公布号 FR2396019(A1) 申请公布日期 1979.01.26
申请号 FR19770020319 申请日期 1977.07.01
申请人 CASSENNE LABORATOIRES 发明人
分类号 A61K35/74;A61K38/00;A61K39/00;A61K39/104;C07K14/21;C12P21/00;(IPC1-7):07G7/028;12K5/00;61K37/02 主分类号 A61K35/74
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