发明名称 acetylated water soluble gluco-peptide prepn. from escherichia coli - used as antiinflammatories and immunostimulant(s)
摘要 <p>Water-soluble acetylated glucopeptides are prepd. from lysed Escherichia coli cells. They have a molecular weight of 1000-200,000 contain >=25% biuretogenic material and >=30% neutral monosaccharides. They do not contain diaminopimelic acid and having a UV absorption maximum at 210 mu. Glucoproteins or molecular wt. >300,000 extracted from lysed E. coli cells are submitted to acetolysis, usually with a mixt. of acetic anhydride acetic acid and sulphuric acid. The crude acetylated prod. is treated with an organic solvent, such as chloroform, and the aq. phase undergoes diafiltration using a porous membrane which retains material of mol. wt. >=1000. The retained material is sepd.</p>
申请公布号 FR2396018(A1) 申请公布日期 1979.01.26
申请号 FR19770020318 申请日期 1977.07.01
申请人 CASSENNE LABORATOIRES 发明人
分类号 A61K35/74;A61K38/00;C07K14/245;C12P21/00;(IPC1-7):07G7/028;61K37/02 主分类号 A61K35/74
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