发明名称 |
Deuterated 1,1-difluoro-2,2-dihaloethyl-difluoromethyl ethers, a process for their preparation and their use in anesthetics. |
摘要 |
<p>A deuterium containing ether corresponding to the formula
<Chemistry id="chema01" num="0001"><Image id="ia01" he="21" wi="30" file="IMGA0001.TIF" imgContent="chem" imgFormat="TIFF" inline="no" /></Chemistry>wherein X is fluoro and X' is bromo or chloro or both X and X' are chloro.</p><p>The compounds are prepared by deuteration of the corresponding undeuterated ethers with D<Sub>2</Sub>0 in the presence of a strong base.</p><p>They are useful as anesthetics and have a lower toxicity than the undeuterated analogues.</p> |
申请公布号 |
EP0000323(A1) |
申请公布日期 |
1979.01.24 |
申请号 |
EP19780100004 |
申请日期 |
1978.06.01 |
申请人 |
THE DOW CHEMICAL COMPANY |
发明人 |
LARSEN, ERIC RUSSELL;MCCARTY, LESLIE PAUL |
分类号 |
A61K31/08;A61P23/00;C07B31/00;C07B59/00;C07C41/00;C07C43/12;C07C67/00;(IPC1-7):07B23/00;61K31/08 |
主分类号 |
A61K31/08 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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