发明名称 3-Endo-protected hydroxyl-tricyclo{8 3,2,0,0{hu 2,7{b {9 -heptan-6-ones
摘要 A novel 3-endo-protected hydroxyl-tricyclo[3,2,0,02,7]-heptan-6-one is described which can be alkylated stereospecifically to give a 5-endo-protected hydroxyl-bicyclo [2,2,1]heptan-2-one which may then be converted via a sequence of reactions into prostaglandins of the F-series having a protecting group at the 9-position. The synthesis of the tricyclo[3,2,0,02,7]heptan-6-one is also described.
申请公布号 US4134911(A) 申请公布日期 1979.01.16
申请号 US19760746741 申请日期 1976.12.02
申请人 ALLEN & HANBURYS LIMITED 发明人 ROBERTS, STANLEY M.
分类号 C07C69/734;A61K31/045;A61K31/20;A61K31/23;A61K31/275;A61P43/00;C07C41/00;C07C43/178;C07C45/00;C07C45/67;C07C49/517;C07C49/753;C07C51/00;C07C51/367;C07C59/62;C07C67/00;C07C69/013;C07C253/00;C07C255/46;C07C401/00;C07C405/00;C07D309/12;C07D311/00;C07F7/18;(IPC1-7):C07F7/18 主分类号 C07C69/734
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