9-(3,5-DI-O-ACYL-BETA-D-ARABINO-FURANOSYL)-ADENINE COMPOUNDS AND PROCESS FOR THEIR PRODUCTION

摘要

9-(3,5-Di-O-acyl- beta -D-arabinofuranosyl)adenine compounds and their production by reacting in each case a 9-(5-O-tri-substituted-silyl-2,3-di-O-acyl- beta -D-arabinofuranosyl)adenine compound with a tetraalkylammonium fluoride. The compounds are useful as antiviral agents. The compounds are stable and being lipophilic are adaptable to long-acting and depot injectable pharmaceutical formulation.