| 摘要 |
2-Isocyanatoalkyl esters of organic carboxylic acids are prepared by reacting (a) an aqueous solution of a 2-oxazoline with (b) an organic solution of phosgene dissolved in a water-immiscible organic solvent in the presence of (c) a hydrochloric acid acceptor. As an example, 2-isocyanatoethyl methacrylate was prepared by concurrently blending an aqueous stream of 2-isopropenyl-2-oxazoline, a methylene chloride stream of phosgene and an aqueous stream of sodium hydroxide at a temperature of from about 0 DEG C. to about 10 DEG C. The reaction rate is very high and the reaction is essentially complete upon blending the reactants. |
