| 发明名称 |
Preparation of {60 -acylacetamides using tetramethyl guanidine condensing agent |
| 摘要 |
A method is described for preparing an alpha -substituted- alpha -acylacetamide wherein an alpha -acyl- alpha -halo-acetamide is allowed to react with an organic compound with pKa between 7 and 12 in a medium of an aprotic solvent and in the presence of a tetraalkylguanidine as basic condensing agent.
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| 申请公布号 |
US4131735(A) |
申请公布日期 |
1978.12.26 |
| 申请号 |
US19750635063 |
申请日期 |
1975.11.25 |
| 申请人 |
AGFA-GEVAERT, N.V. |
发明人 |
VAN POUCKE, RAPHAEL K.;BAEYENS, FREDDY C.;MORTELMANS, PAUL A. |
| 分类号 |
C07C317/34;C07D239/90;C07D473/08;C07D521/00;G03C7/305;(IPC1-7):C07D235/00;C07D239/72;C07D253/06;C07D253/04 |
主分类号 |
C07C317/34 |
| 代理机构 |
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