发明名称 |
Protein growth factor related to TNF-beta and coupled with a toxic moiety for use in treating prostate cancer |
摘要 |
Use of an isolated or recombinant protein that selectively inhibits the proliferation of androgen-independent prostate cancer cells. Also disclosed is a composition for treating androgen-independent prostate cancer, the composition containing the before-mentioned protein coupled to a toxic moiety. The toxic moiety is selected from the group consisting of ricin, tetanus and diphtheria.
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申请公布号 |
NZ334592(A) |
申请公布日期 |
2000.10.27 |
申请号 |
NZ19970334592 |
申请日期 |
1997.09.11 |
申请人 |
ORTHO-MCNEIL PHARMACEUTICAL, INC |
发明人 |
ERLANDER, MARK;HUANG, SHAOMING;JACKSON, MICHAEL;PETERSON, PER |
分类号 |
C12N15/09;A61K38/00;A61K38/55;A61K48/00;A61K51/00;A61P35/00;C07K14/495;C07K14/525;C12N15/16;(IPC1-7):A61K38/18;C12N15/18;A61K35/74 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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