| 摘要 |
beta -Lactam compounds of the formula <IMAGE> in which A is hydrogen or methoxy, B is phenyl; phenyl substituted by at least one of hydroxyl, halogen, methoxy, -CN and CH3-SO2-; thienyl; cyclohexenyl; 1,4-cyclohexadien-1-yl; or furyl; E is oxygen or sulphur; n is 1 or 2, Y is <IMAGE> or a salt thereof, in which the carbon atom which carries the carboxyl group is bonded to the nitrogen atom of the beta -lactam ring, T is hydrogen, alkyl-CO-O-, hydroxyl-, pyridinium, aminopyridinium, carbamoyloxy, azido, cyano, optionally N-substituted thiocarbamoylthio, optionally substituted S-phenyl, or a -S-Het group, Het is an optionally substituted heterocyclic 5-membered or 6-membered ring; U is oxygen, sulphur or -CH2-; and Z is an optionally substituted aromatic or pseudoaromatic ring which contains at least one nitrogen atom via which it is bonded to the N3 of the imidazolidinone radical of the beta -lactam, are suitable as antibiotics, growth promoters for animals and preservatives. |
