NITROGENATED AROMATIC HETEROCYCLIC COMPOUND AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME

摘要

Disclosed are: a novel compound having one or both of a xanthine oxidase inhibitory activity and an uric acid excretion promoting activity; a pharmaceutical composition comprising the compound as an active ingredient; use of the compound for medical purposes; and others. The compound is a nitrogenated aromatic heterocyclic compound represented by the general formula (1-A) or a pharmaceutically acceptable salt thereof: (1-A) wherein X<SUP>1a</SUP> and X<SUP>2a</SUP> independently represent -CH= or -N=; R<SUP>1a</SUP> and R<SUP>2a</SUP> independently represent an alkyl group which may be substituted, an aryl group which may be substituted, or the like; R<SUP>3a</SUP> represents a hydrogen atom, a halogen atom or an alkyl group; and R<SUP>4a</SUP> represents a 5-tetrazolyl group or a carboxyl group.