G-RICH POLYNUCLEOTIDES FOR THE TREATMENT OF HUNTINGTON'S DISEASE
摘要
<p>The present invention relates to oligonucleotide compositions and therapeutic uses thereof to modify protein-protein interactions. In particular, the invention relates to the use of a guanidine-rich oligonucleotides to disrupt disease-causing protein aggregates, for example, Huntington's Disease (HD) protein aggregates.</p>
申请公布号
WO2007044851(A2)
申请公布日期
2007.04.19
申请号
WO2006US39921
申请日期
2006.10.06
申请人
UNIVERSITY OF DELAWARE;KMIEC, ERIC, B.;PAREKH-OLMEDO, HETAL