PHOSPHONIC ACID SUBSTITUTED AROMATIC STEROIDS AS INHIBITORS OF STEROID 5–-REDUCTASE

摘要

PHOSPHONIC ACID SUBSTITUTED AROMATIC STEROIDS AS INHIBITORS OF STEROID 5-.alpha.-REDUCTASE Invented are phosphonic acid substituted analogues of steroidal synthetic compounds, pharmaceutical compositions containing these compounds, and methods of using these compounds to inhibit steroid 5-.alpha.-reductase, including using these compounds to reduce or maintain prostate size. Also invented are intermediates used in preparing these compounds.