发明名称 CIS-4,5-Didehydro-13,14-didehydro-11-deoxy-PGF{HD 1{B {60 {0 compounds
摘要 This invention comprises certain analogs of the prostaglandins in which the double bond between C-13 and C-14 is replaced by a triple bond. Also provided in this invention, are novel chemical processes and novel chemical intermediates useful in the preparation of the above prostaglandin analogs. These prostaglandin analogs exhibit prostaglandin-like activity, and are accordingly useful for the same pharmacological purposes as the prostaglandins. Among these purposes are blood pressure lowering, labor induction at term, reproductive-cycle regulation, gastric antisecretory action, and the like.
申请公布号 US4126753(A) 申请公布日期 1978.11.21
申请号 US19770820973 申请日期 1977.08.01
申请人 THE UPJOHN COMPANY 发明人 SMITH, HERMAN W.
分类号 A61K31/23;A61P43/00;C07C35/27;C07C51/347;C07C51/60;C07C53/21;C07C57/30;C07C57/72;C07C67/00;C07C401/00;C07C405/00;C07D307/935;C07D317/14;C07F9/38;C07F9/40;C07F9/54;(IPC1-7):C07C177/00 主分类号 A61K31/23
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