| 发明名称 |
THERAPIE MIT LIPOPROTEINLIPASE (LPL) VARIANT |
| 摘要 |
<p>The invention provides for the use of a therapeutic derived from a truncated lipoprotein lipase protein (LPL S447X), including nucleic acids encoding such proteins, for the treatment of conditions including LPL responsive conditions, such as cardiovascular disease, hypertension, LPL deficiency, high triglyceride levels, low HDL-cholesterol levels or atherosclerosis.</p> |
| 申请公布号 |
DE60039880(D1) |
申请公布日期 |
2008.09.25 |
| 申请号 |
DE2000639880 |
申请日期 |
2000.06.23 |
| 申请人 |
AMSTERDAM MOLECULAR THERAPEUTICS B.V.;THE UNIVERSITY OF BRITISH COLUMBIA |
发明人 |
HAYDEN, MICHAEL R.;KASTELEIN, JOHN J.;EXCOFFON, KATHERINE JULIA DIANE |
| 分类号 |
A61K38/46;C12N15/09;A61K35/76;A61K48/00;A61P3/04;A61P3/10;A61P9/00;A61P9/04;A61P9/10;A61P9/12;A61P43/00;C12N9/20;C12N15/63 |
主分类号 |
A61K38/46 |
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