发明名称 |
COMPOSITIONS AFFECTING HYALURONIC ACID MEDIATED ACTIVITY |
摘要 |
Compositions comprising hyaluronic acid (HA) or agents that interfere with HA binding of HA receptors and methods of using the same are provided. For example, there is provided a composition comprising HA oligomers ranging in size from 10-mer to 80-mer and use of the same for promoting migration, growth or survival of wild-type or transformed/cancerous cells. There is also provided a composition comprising an agent that interferes with binding between an HA oligomer of a size of about 10-mer to about 80-mer and an HA receptor. Such compositions may be useful for therapeutic, diagnostic or imaging applications. Examples of therapeutic use are wound repair or cancer treatment. |
申请公布号 |
CA2702366(C) |
申请公布日期 |
2016.06.07 |
申请号 |
CA20082702366 |
申请日期 |
2008.10.10 |
申请人 |
LONDON HEALTH SCIENCES CENTRE RESEARCH INC.;REGENTS OF THE UNIVERSITY OF MINNESOTA |
发明人 |
TURLEY, EVA;MCCARTHY, JIM;TOLG, CORNELIA;LUYT, LEONARD G. |
分类号 |
C08B37/08;A61B6/00;A61K9/70;A61K31/728;A61K38/10;A61L15/44;A61L17/00;A61P17/02;A61P35/00;C08L5/08;G01N33/53;G01T1/161 |
主分类号 |
C08B37/08 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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