发明名称 |
GESCHUETZTE AMINOSAEUREN ODER PEPTIDE |
摘要 |
<p>In an amino acid having omega -amino group protected with a protective group or a peptide having the residue of such a protected amino acid, the improvement according to which the protective group is p-methylbenzylsulfonyl group. The omega -amino acids protected with p-methylbenzylsulfonyl or the peptides having residues of such protected amino acids are useful for production of various peptides by liquid phase method as well as by solid-phase method, because the protective group has specific selectivity of remaining stable under the conditions commonly employed in the removal of alpha -aminoprotecting group but is cleaved smoothly in a good yield by hydrogen fluoride without exerting untoward unfluences upon peptides.</p> |
申请公布号 |
DE2817208(A1) |
申请公布日期 |
1978.11.02 |
申请号 |
DE19782817208 |
申请日期 |
1978.04.20 |
申请人 |
TAKEDA CHEMICAL INDUSTRIES,LTD. |
发明人 |
FUJINO,MASAHIKO;FUKUDA,TSUNEHIKO;KITADA,CHIEKO |
分类号 |
C07K1/06;C07C67/00;C07C301/00;C07C303/38;C07C309/81;C07C311/13;(IPC1-7):C07C103/52;C07C101/02 |
主分类号 |
C07K1/06 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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