摘要 |
PROBLEM TO BE SOLVED: To provide extracorporeal methods for the treatment of a subject having a pregnancy related hypertensive disorder, such as pre-eclampsia or eclampsia, and devices used for the extracorporeal treatment of subjects having a pregnancy related hypertensive disorder, such as pre-eclampsia or eclampsia.SOLUTION: A method comprises: using an apheresis procedure for removing a specific component from the blood, plasma, serum, or a fraction thereof, of a subject; including an agent that binds to positively charged proteins (e.g., lipoprotein, apolipoprotein, fibrinogen, globulin, and C reactive protein); and reducing the level of sFlt-1 in a subject. The agent includes dextran sulfate or anionic polyacrylate and is immobilized with a water-insoluble porous carrier.SELECTED DRAWING: None |