发明名称 |
2-Halo-4-aminomethyl-6-alkyl-3-pyridinols useful as diuretics in treating hypertension and edema |
摘要 |
Certain substituted 4-aminomethyl-3-pyridinols and their pharmaceutically acceptacle acid addition salts wherein the pyridinol nucleus may be further substituted with 1 to 2 nuclear substituents are useful as antihypertensive, diuretic and saluretic agents. These products may be prepared by halogenating an appropriately substituted pyridine salt.
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申请公布号 |
US4123537(A) |
申请公布日期 |
1978.10.31 |
申请号 |
US19770800973 |
申请日期 |
1977.05.26 |
申请人 |
MERCK & CO., INC. |
发明人 |
SMITH, ROBERT L.;STOKKER, GERALD E.;GRAGOE, JR., EDWARD J. |
分类号 |
F25D21/06;A47F3/04;C07D213/65;C07D213/84;C07D263/42;(IPC1-7):A61K31/34 |
主分类号 |
F25D21/06 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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