发明名称 Hydrazones of 3-formyl rifamycin - as antibiotics and dna polymerase inhibitors
摘要 <p>Cpd. (I) and their 16, 17, 18, 19, 28, 29-hexahydro and 27-demethoxy-27-hydroxy derivs. (where R1, and R2 are H, alkyl, alkenyl, alkynyl, aryl, aralkyl, heterocyclyl or cycloalkyl, provided that when one of R1 and R2 is H, or 1-4C alkyl the other may be unsubstd. alkyl or hydroxyalkyl having at least 5C or substd. alkyl other than dimethylaminoethyl or alkenyl, alkynyl, aryl, aralkyl, heterocyclyl or cycloalkyl wherein aryl is not phenyl or p-carboxyphenyl and aralkyl is not benzyl, and R3 is H or Ac) are prepd. from 3-formylrifamycin and H2NNR1R2.</p>
申请公布号 NL7807456(A) 申请公布日期 1978.10.31
申请号 NL19780007456 申请日期 1978.07.11
申请人 GRUPPO LEPETIT S.P.A. TE MILAAN, ITALIE. 发明人
分类号 C07D498/08;(IPC1-7):07D498/18;61K31/395 主分类号 C07D498/08
代理机构 代理人
主权项
地址