VAL27, ALA29-SALMON CALCITONIN

摘要

This invention relates to a polypeptide of the formula Í! and acid addition salts and complexes thereof. The polypeptide of the formula Í! has serum calcium reducing activity, and as tests upon rats have shown, it has an activity of 3700 - 6000 MRC units for serum calcium reducing activity. It has an activity which is fifteen times higher than that of human calcitonin and sheep calcitonin and twenty times higher than that of porcine or cattle calcitonin. The said activity is the same or higher as compared with the most active of known salmon calcitonin.