发明名称 2-Decarboxy-2-amino-methyl-9-deoxy-9-methylene-PGF-type compounds
摘要 This invention comprises certain analogs PGE or 11-deoxy-PGE compounds in which the carbonyl at C-9 is replaced by methylene. Also provided in this invention, are novel chemical processes and novel chemical intermediates useful in the preparation of the above prostaglandin analogs. These prostaglandin analogs exhibit prostaglandin-like activity, and are accordingly useful for the same pharmacological purposes as the prostaglandins. Among these purposes are blood pressure lowering, labor induction at term, reproductive-cycle regulation, gastric antisecretory action, and the like.
申请公布号 US4119666(A) 申请公布日期 1978.10.10
申请号 US19770832243 申请日期 1977.09.12
申请人 THE UPJOHN COMPANY 发明人 BUNDY, GORDON L.
分类号 A61K31/045;A61K31/13;A61K31/19;A61K31/557;A61K31/5575;A61P43/00;C07C67/00;C07C401/00;C07C405/00;C07D311/94;C07D313/00;(IPC1-7):C07C87/45;C07C87/50;C07C177/00 主分类号 A61K31/045
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